The central square of Trikala, officially Plateia Iroon Polytechneiou, occupies the point where the modern city meets the Litheos River, pedestrian shopping streets and the older commercial centre. Its roughly five stremmata of public space have carried a succession of names and designs, reflecting changes from Ottoman market town to contemporary Thessalian city.
Municipal history records that the area was known as Pazar Mosque during Ottoman rule, when a mosque and weekly market defined its role. After Thessaly joined the Greek state, the square received names including Union Square in 1907, 4th of August Square in 1937 and Americans Square after the Second World War. Its present dedication commemorates the students of the Athens Polytechnic uprising.